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February 2005

Comparison of Far Field R-Wave Sensing in the Atrial Appendage between the Medtronic Model 10636 and the Medtronic Model 5076

Principal Investigator: Seth J. Worley, MD

Collaborators: Douglas C. Gohn, MD & Ward Pulliam, MD

Sponsor: Medtronic

Objective: Patients who require implantation of a dual chamber or biventricular ICD are randomized to receive either the FDA approved 5076 lead or the investigational 10636 lead in the atrium. The 10636 lead has 4 mm tip to ring spacing (as opposed to 10 mm) and the study is designed to demonstrate that this difference will reduce far filed R-wave amplitudes and will not alter P-wave amplitudes.


Measuring the Impact of a Multidisciplinary Oncology Program on the Clinical Outcomes of Patients with Thoracic Malignancy.

Principal Investigator: Amy Jo Pixley, BSN, RN

Collaborators: Jeffrey T. Cope, MD; Jeffrey Eshleman, MD; G. Thomas O’Conor, Jr., MD; Gregory T. Rossini, MD

Sponsor: LL Flemming Trust

Objective: To measure the impact of a comprehensive multidisciplinary thoracic oncology program on the clinical outcomes of patients diagnosed with thoracic malignancy, with an assigned RN coordinator to expedite patient diagnosis, enhance treatment plan development and provide coordinated delivery of information, support and services to a defined patient population.


LV Lead Comparison Study

Principal Investigator: Seth J. Worley, MD

Collaborators: Douglas C. Gohn, MD & Ward Pulliam, MD

Sponsor: Medtronic

Objective: The purpose of this study is to compare the Attain 2187 LV lead to the Attain 4194 LV lead in patients receiving a resynchronization device for the ability to be placed in the target vessel, stability, pacing thresholds, phrenic pacing, and final lead position.